RYAN THOMAS FLYNN

March 26, 2013

1. EDUCATIONAL AND PROFESSIONAL HISTORY
   
   
   1. List of institutions attended, board certification, licensure
      
      

      2002	B.A. Luther College, Decorah, IA
      	Physics and Mathematics (Magna Cum Laude)
      2004	M.S. University of Wisconsin-Madison
      	Medical Physics
      2007	Ph.D. University of Wisconsin-Madison
      	Medical Physics

      
      Board Certification
      
      

      5/2011

      American Board of Radiology: Therapeutic Medical Physics

      
      
   2. Professional and Academic Positions
      
      

      Jan. – May 2004	Teaching Assistant, Department of Medical Physics, University of Wisconsin-Madison, Madison, WI
      Mar. – June 2005	Guest Scientist, Department of Medical Physics in Radiation Oncology, The German Cancer Research Center (DKFZ), Heidelberg, Germany
      Sept. – Dec. 2006	Guest Lecturer, Department of Medical Physics, University of Wisconsin-Madison, Madison, WI
      Sept. – Dec. 2006	Medical Physics Intern, Department of Radiation Oncology, Turville Bay MRI & Radiation Oncology Center, Madison, WI
      Sept. 2002 – Dec. 2007	Research Assistant, Department of Medical Physics, University of Wisconsin-Madison, Madison, WI
      Dec. 2007 – present	Adjunct Professor, Department of Medical Physics, University of Wisconsin-Madison, Madison, WI
      Dec. 2007 – present	Clinical Assistant Professor, Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA
      July 2010 – present	Technical Director of Proton Therapy, University of Iowa

      
      
   3. Honors and Awards
      
      

      5/2002	Phi Beta Kappa member
      4/2006	First Prize, student scientific presentation, North Central Chapter of the American Association of Physicists in Medicine Bi-Annual Meeting
      5/2007	University of Wisconsin Vilas Travel Fellowship for Proton Therapy Co-Operative Group (PTCOG) Meeting in Zibo, China
      5/2007	PTCOG Travel Fellowship for meeting in Zibo, China
      10/2009	U. Iowa Rad. Onc. Clinical Trial Research Award for patient accrual
      3/2010	Iowa Center for Research by Undergraduates (ICRU) Distinguished Mentor Award Certificate, Announcement
      11/2010	Iowa Centers for Enterprise Elevator Pitch Competition: 1st (of 36). $10,000 prize. Certificate

   Other honors

   1. May 2009 - Selected by David Nelms to attend Honors Presidential Dinner at President Mason's Residence
   2. May 2012 - Selected by Drake Edwards to attend Honors Presidential Dinner at President Mason's Residence
      
      
   
   
2. TEACHING
   
   
   1. Teaching assignments on a semester by semester basis
      
      

      Year	Clinical Teaching	Hours/year
      2008 - present	Linear accelerator quality assurance	40
      2008 - present	Portal imaging for treatment verification (rotation)	40
      2008 - 2010	High/low dose rate brachytherapy planning and delivery	120
      2008 - present	External beam radiation delivery procedures	40

      
      

      Year	Classroom, Seminar, or Lab	Classroom Hours/year	Slides / Evaluations
      2008, 2010, 2012	Medical Physics 077:211	2 - 3	Link
      2009, 2011	Radiation Oncology Medical Physics Lecture Series	10.5	Link
      2009, 2011, 2012	Foundations of Clinical Practice I: Case based learning	30, 12, 6	Link
      2010	Radiation Oncology for RTTs Lecture Series	1.5	Link
      2010	Imaging physics for diagnosis and radiation therapy	14	Link

      
      
   2. Students and Trainees Supervised
      
      Medical Physics Residents
      

      Name	Dates	Position following UI graduation
      Hemant Shukla	12/2007 - 4/2008	Medical physicist at St. Francis Medical Center, Peoria, IL
      Earl Nixon	12/2007 - 7/2008	Medical physicist at UIHC
      William Kearney	12/2007 - 10/2010
      Xiaofei Ying	4/2008 - 7/2010	Medical physicist at Delaware County Regional Cancer Center
      Vibha Chaswal	7/2008 - 7/2010
      Junyi Xia	7/2009 - 7/2011	Faculty Medical Physicist, University of Iowa
      Yunfei Huang	1/2010 - Present
      Daniel Hyer	7/2010 - Present
      Christopher Mart	7/2011 - Present
      Patrick Hill	7/2012 - Present

      
      Medical Residents
      

      Name	Dates	Position following UI graduation
      Samuel Andrews	10/2008 - 12/2008 3/2009 - 7/2009	Private practice, Rockford, IL

      
      Graduate Students
      

      Name	Dates	Institution
      Wenjun Yang	9/1/2010 - present	UIHC - Department of Biomedical Engineering Research advisor on M.S. thesis committee, April 2012
      Xing Li	8/15/2011 - present	UIHC - Department of Physics

      
      Medical Students
      

      Name	Dates	Institution
      Elizabeth Breitbach	5/2012 - 9/2012	UI Carver College of Medicine
      Quentin Adams	5/2012 - 9/2012	UI Carver College of Medicine

      
      Undergraduates
      

      Name	Dates	UI Dept.	Position following UI graduation
      David Nelms	5/2008 - 8/2009	Physics	UI Carver College of Medicine
      Justin Jian Guan	5/2009 - 8/2009	BME	UI Carver College of Medicine
      Adam Schwertner	9/2009 - 7/2010	BME	University of Chicago Pritzker School of Medicine
      Drake Edwards	9/2009 - present	Physics
      Elizabeth Breitbach	6/2010 - 8/2011	BME	UI Carver College of Medicine
      Jeff Moon	8/2011 - 5/2012	BME
      Jingzhu Xu	5/2012 - present	BME

      
      Interns
      

      Name	Dates	Institution
      Julia Hartmann	10/2008	Siemens Oncology Care Systems
      Jared Stiles	1/2010-3/2010	UIHC

      
      
   3. Other contributions to institutional programs
      
      

      Year	Contribution	Hours/year
      2008 - present	Medical physics journal club (UIHC)	10
      2010, 2011, 2012	BME Senior Design Group Mentor	40
      2011- present	Iowa Medical Innovation Group	40

      
      
   4. Honors theses
      
      

      Student	Title	Year	Theses
      David W. Nelms	Assessment of three simple methods for dead detector correction in cone beam computed tomography	2009	Link
      Justin Jian Guan	Management of megavoltage cone beam computed tomography (MVCBCT) imaging dose for head and neck cancer patients	2010	Link
      Jeff Moon	Development of novel nano-cocrystal contrast agents for potential use in diagnostic imaging	2012	Link
      Drake Edwards	Development of an apparatus and method for treating cancerous tumors through multiple rotating shield brachytherapy (M-RSBT)	2012	Link

      
      
3. CLINICAL
   
   

   Procedure implementation

   1. 2008 - Documented vaginal cylinder brachytherapy procedures. PDF
   2. 2008 - Established paperless workflow for prostate seed implant procedures. PDF
   3. 2008 - Established clinical workflow for imaging beam line usage for patient positioning for Dosimetry and Medical Physics divisions.
   4. 2009 - Established prone breast radiotherapy workflow at UIHC. PDF
   5. 2009 - Established clinical workflow for MVCBCT imaging withnew ultrafast ceramic scintillator system. PDF
   6. 2010 - Established total skin electron therapy (TSET) program at UIHC under guidance of Tim Waldron, M.S. PDF
      
      

Proton Therapy

1. Request for proposal submitted Jan 26, 2011. Appendix. Note: Largest medical equipment RFP in UIHC history.
2. Executive Report from June 14, 2012.
   
   

Other

1. 8/16/2010 - Assembled data to obtain RTOG approval for Image Guided Radiation Therapy (IGRT) trials. (RTOG # 1101; NCI # IA018; RTF # 2595)
   
   
4. SCHOLARSHIP
   
   
   1. Dissertation
      
      A comparison of intensity modulated x-ray therapy to intensity modulated proton therapy for the delivery of non-uniform dose distributions (PDF)
      
      
   2. Peer-reviewed papers
      
      
      Published
      1. Flynn RT, Barbee DL, Mackie TR, Jeraj R.  Comparison of intensity modulated x-ray therapy (IMXT) and intensity modulated proton therapy (IMPT) for selective subvolume boosting: a phantom study.  Phys Med Biol, 52, 6073-6091 (2007). PMCID: PMC2712448.
         I designed and performed the study and analysis and completed the majority of the writing.
      2. Kissick MW, Flynn RT, Westerly DC, Mackie TR, Hoban PW. On the making of sharp longitudinal dose profiles with helical tomotherapy. Phys Med Biol, 52, 6497-6510 (2007), PMCID: PMC2220158.
         I was involved in refining the theoretical and experimental approach used for this paper. I wrote the computer code used to generate and analyze the data. I contributed to writing the paper in the drafting stages.
      3. Flynn RT, Kissick MW, Jeraj R, Mehta MP, Olivera GH, Mackie TR. The impact of linac output variations on dose distributions in helical tomotherapy.  Phys Med Biol, 53, 417-430 (2008). PMCID: PMC2713685.
         I designed and performed the study and analysis and completed the majority of the writing.
      4. Flynn RT, Bowen SR, Bentzen SM, Mackie TR, Jeraj R. Intensity modulated x-ray (IMXT) vs. proton (IMPT) therapy for theragnostic hypoxia-based dose painting. Phys Med Biol, 53, 4153-4167 (2008), PMCID: PMC2695924.
         I designed and performed the study and analysis and completed the majority of the writing.
      5. Kissick MW, Flynn RT, Westerly DC, Hoban PW, Mo Xiaohu, Soisson ET, McCall KC, Mackie TR, Jeraj R. On the impact of longitudinal breathing motion randomness on tomotherapy delivery. Phys Med Biol 53, 4855-4873 (2008), PMCID: PMC2610272.
         I was involved in refining the theoretical and experimental approach used for this paper. I wrote the computer code used to generate and analyze the data. I contributed to writing the paper in the drafting stages.
      6. Caporaso GJ, Mackie TR, Sampayan S, Chen Y-J, Blackfield D, Harris J, Hawkins S, Holmes C, Nelson S, Paul A, Poole B, Rhodes M, Sanders D, Sullivan J, Wang L, Watson J, Reckwerdt PJ, Schmidt R, Pearson D, Flynn R, Matthews D, Purdy J, "A compact linac for intensity modulated proton therapy based on a dielectric wall accelerator," Phys Med 24, 98-101 (2008). PDF.
         I was involved in the process of proposing innovative approaches for delivering proton therapy with the Dielectric Wall Accelerator (DWA), but did not contribute significantly to the writing of this paper.
      7. Bowen SR, Flynn RT, Bentzen SM, Jeraj R, On the sensitivity of IMRT dose optimization to the mathematical form of a biological imaging-based prescription function. Phys Med Biol 54, 1483-1501 (2009). PMCID: PMC2858011.
         I wrote the computer code used to do the radiation dose calculations and treatment planning that comprised the results presented in this paper. I also mentored the first author throughout the data generation and manuscript preparation processes.
      8. Flynn RT, Hartmann J, Bani-Hashemi A, Nixon E, Siochi RAC, Pennington EC, Bayouth JE. Dosimetric characterization and application of an imaging beam line with a carbon electron target for megavoltage cone beam computed tomography. Med Phys 36, 2181-2192 (2009). PDF.
         I designed and performed the study and analysis and completed the majority of the writing.
      9. Nelms DW, Shukla HI, Nixon E, Bayouth JE, Flynn RT, Assessment of three dead detector correction methods for cone beam computed tomography. Med Phys 36, 4569-4576 (2009). PDF.
         I designed the study, wrote the majority of the computer code used for data generation and analysis, was the mentor of the first author.
      10. Barbee DL, Flynn RT, Holden JE, Nickles RJ, Jeraj R, Partial volume correction of PET-imaged tumour heterogeneity using expectation maximization with a spatially varying point spread function, Phys Med Biol 55, 221-236 (2010).
          I was involved in refining the theoretical and experimental approaches used for this paper, and contributed to writing the manuscript and responding to reviewer criticism.
      11. Flynn RT, Loss of radiobiological effect of imaging dose in image guided radiotherapy due to prolonged imaging-to-treatment times, Med Phys 37, 2761-2769 (2010). PDF.
          I designed and performed the study and analysis and completed the majority of the writing.
      12. Breitbach EK, Maltz JS, Gangadharan B, Bani-Hashemi A, Anderson CM, Bhatia SK, Stiles J, Edwards DS, Flynn RT, Image quality improvement in megavoltage cone beam CT using an imaging beam line and a sintered pixelated array system, Med Phys 38, 5969-5979 (2011). PDF.
          I designed the study, acquired some of the data, performed some of the analysis, and completed a significant portion of the writing.
      13. Sun W, Bhatia SK, Jacobson GM, Flynn RT, Kim Y, Target volume changes through high-dose-rate brachytherapy for cervical cancer when evaluated on high resolution (3.0 Tesla) magnetic resonance imaging, Practical Radiation Oncology, 2, e101-e106 (2012).
          
          I provided scientific input into the interpretation of data and edited the manuscript for content, grammar, and word usage.
          
      14. Kissick MW, Flynn RT, Mo X, Campos DD, Mackie TR, Yan Y, Zhao D, Probabilistic optimization should be efficacious for tomotherapy, Journal of Applied Clinical Medical Physics 13(5), 155-169, (2012).
          
          I wrote the computer code used to generate the major computational results of the paper.
          
      15. Zhang M, Flynn RT, Mo X, Mackie TR, The energy margin strategy for reducing dose variation due to setup uncertainty in intensity modulated proton therapy (IMPT) delivered with distal edge tracking (DET), Journal of Applied Clinical Medical Physics, 13(5), 170-180 (2012).
          
          I wrote the computer code used to generate some of the major computational results of the paper,provided scientific input into the intepretation of the data, and edited the manuscript for content, grammar, and scientific soundness.
      16. Westerly DC, Shefter T, Kavanagh B, Chao E, Lucas D, Flynn R, Miften M, High-dose MVCT image guidance for SBRT, Med Phys 39, 4812-4819 (2012).
          I wrote the computer code used to generate the modulation transfer function and contrast-to-noise ratio results, provided scientific input into the intepretation of the data, and edited the manuscript for content and scientific soundness. PDF
      17. Enger SA, Fisher DR, Flynn RT, Gadolinium-153 as a Brachytherapy Isotope, Phys Med Biol, 58, 957-964 (2012).
          I conceived Gd-153 brachytherapy and wrote the Introduction and half of the Materials and Methods section of the paper.
      18. Huang Y, Flynn RT, Siochi AC, Bayouth JE, "Equivalent Quality of Unflattened Photon Beam Modeling, Planning, and Delivery," Accepted for publication in the Journal of Applied Clinical Medical Physics, 2/7/2013.
          I wrote the computer code used to quantify the equivalence of the treatment plans in three dimensions, provided scientific input into the intepretation of the data, and edited the manuscript for content and scientific soundness.
      
      

   Submitted

   1. Huang Y, Flynn RT, Siochi AC, Bayouth JE, "Prediction of delivery time and gating window for gated radiotherapy," Submitted to Int J Rad Oncol*Biol*Phys May 17, 2011.
   2. Yang W, Kim Y, Wu X, Song Q, Liu Y, Bhatia SK, Sun W, Flynn RT, "Rotating-shield brachytherapy for cervical cancer," Submitted to Radiotherapy and Oncology December 19, 2012.

   Under revision

   1. Becker SJ, Flynn RT, "Collision indicator charts for gantry-couch position combinations for Siemens Oncor linacs," Submitted to JACMP June 11, 2012.
   2. Liu Y, Flynn RT, Yang W, Kim Y, Wu X, "Rapid Emission Angle Selection in Rotating-Shield Brachytherapy," Submitted to Medical Physics Oct. 2012. Under revision.
   3. Anderson J, Xia J, Flynn RT, Modrick JM, Bhatia SK, Jacobson GM, Kim Y, "High Resolution (3 Tesla) MRI-Guided, Conformal Brachytherapy for Cervical Cancer:
      Consequences of Different High-Risk CTV Sizes," Submitted to Practical RAdiation Oncology, Under Revision.
      
   3. Patents
      
      
      1. Mackie TR, Flynn RT, Kissick MW, Al-Sadah JH, Westerly DC, Hill PM, "Phantom for heavy ion range detection," US Patent 7,714,309.
      2. Flynn RT, Mackie TR, "Ion radiation therapy system with variable beam resolution," US Patent 7,763,873.
      3. Flynn RT, Mackie TR, "System and method for optimization of a radiation therapy plan in the presence of motion," US Patent 7,856,082.
      4. Westerly DC, Mackie TR, Flynn RT, "Scanning aperture ion beam modulator," US Patent 7,977,648.
      5. Flynn RT, Mackie TR, "Ion radiation therapy system with distal gradient tracking," US Patent 7,977,657.
      6. Mackie TR, Kissick MW, Flynn RT, "Ion radiation therapy system with rocking gantry motion," US Patent 8,093,568.
      7. Flynn RT, Mackie TR, "Ion radiation therapy system with variable beam resolution," US Patent 8,154,001.
         
         

      Provisional Patent Applications

      1. Flynn RT, Kwiatkowski A, Edwards D, "Advanced Rotating Shield Brachytherapy," Filed with USPTO July 31, 2012.
      2. Liu Y, Wu X, Flynn RT, "Advanced Rotating Shield Brachytherapy and Planning of Same," Filed with USPTO August 2012.
      3. Flynn RT, Enger SA, "Radiation Source Wire for High-Dose-Rate Brachytherapy with Gadolinium-153," Filed with USPTO Dec. 20, 2012.
         

      Patent Applications Submitted to USPTO

      1. Flynn RT, Kim Y, Li X, Yuen K-H, "Compensator-based brachytherapy," Filed with USPTO May 8, 2012. Files.
         
         
   4. Book Chapters
      
      
      1. Bayouth JE, Flynn RT, Smith MC, "Megavoltage cone-beam computed tomography-guided intensity modulated radiation therapy in a prostate cancer patient treated on a Siemens Oncor Linear Accelerator" in Image-Guided Radiation Therapy: A Clinical Perspective, 1st ed., editors: Arno J. Mundt and John C. Roeske, 2011.
         PDF
         
         
         
   5. Areas of Research Interest and Current Projects
      
      
      1. Improving megavoltage cone beam computed tomography image quality
      2. Imaging dose management in image guided radiation therapy
      3. High dose rate stereotactic body radiation therapy
      4. Proton radiation therapy
      5. Intensity modulated brachytherapy
         
         
   6. Institutional Review Board approved trials
      
      
      1. Evaluation of a modified radiation therapy imaging beam line
         PI: RT Flynn (University of Iowa) 2008 - 2010
         PDF
      2. Evaluation of an efficient detector for the megavoltage cone beam computed tomography (MVCBCT) patient positioning system
         PI: RT Flynn (University of Iowa) 2009 - 2010
         PDF
         
         
   7. Funding
      
      
      Awarded
      1. American Cancer Society (ACS) Seed Grant IRG-77-004-31
         Intensity modulated brachytherapy for the treatment of cervical cancer
         July 1, 2010 - June 30, 2011, $30,000
         Principal investigator: Ryan Flynn, Co-PIs: Yusung Kim, Geraldine Jacobson, Xiaodong Wu
         PDF
      2. ICTS Clinical & Translational Science Award
         Nano-Cocrystal Contrast Agents
         June 1, 2011 - May 31, 2012, $50,000
         Principal investigator: Leonard MacGillivray, Co-investigtor: Ryan Flynn
         PDF
      3. American Cancer Society (ACS) Seed Grant IRG-77-004-34
         Rotating-shield intensity modulated brachytherapy for cervical cancer
         July 1, 2011 - June 30, 2012, $30,000
         Principal investigator: Ryan Flynn, Co-investigators: Yusung Kim, Ph.D., Geraldine Jacobson, Ph.D.
         PDF
      4. Grow Iowa Values Fund (GIVF)
         Reducing invasiveness and increasing access to tumor conformal brachytherapy for cervical cancer
         Spring 2012, $36,701.28
         Principal investigator: Ryan Flynn
         PDF
      5. ICE Commercialization GAP Fund Program 2012
         Prototype System Development for Interstitial Rotating Shield Brachytherapy of Prostate Cancer
         Jan 1, 2013 - Dec 31, 2013, $75,000
         Principal investigator: Ryan Flynn (0% effort)
         
         PDF

   Small Grants (<$10,000) Received

   1. Iowa Center for Research by Undergraduates (ICRU)
      Summer 2008 - Spring 2009 funding of David Nelms ($5000.00)
      Summer 2009 funding for Justin Jian Guan ($2500.00)
      Fall 2009 - Spring 2010 funding for Adam Schwertner ($2500.00)
      Summer 2010 - Spring 2011 funding for Elizabeth Breitbach ($5000.00)
      Fall 2010 - Spring 2011 funding for Drake Edwards ($2500.00)
      Fall 2011 - Spring 2012 funding for Drake Edwards ($2500.00)
      Summer 2012 - Spring 2013 funding for Jingzhu Xu ($5,000)
   2. Medical Student Research Fellowships (Carver College of Medicine)
      Summer 2009 funding for David Nelms ($5,000)
      Summer 2012 funding for Elizabeth Breitbach ($5,000)
      Summer 2012 funding for Quentin Adams ($5,000)
      

   Pending responses

   1. DOD Idea Development Award - Prostate Cancer Research Program
      Interstitial Rotating Shield Brachytherapy for Prostate Cancer
      2012 - 2014, $324,000
      PI: Ryan Flynn (8% effort)

   Applied for, but not awarded

   1. NIH Clinical & Translational Science Award
      Compensator-based intensity modulated brachytherapy for cervical cancer
      June 1, 2011 - May 31, 2012, $50,000
      Principal investigator: Ryan Flynn, Ph.D.
   2. Mary Kay Foundation Innovation / Translational Cancer Research Grant
      Compensator-based intensity modulated brachytherapy for cervical cancer
      July 1, 2011 - June 30, 2013, $100,000
      PI: Ryan Flynn
   3. American Association of Physicists in Medicine Seed Grant
      Compensator-based intensity modulated brachytherapy for cervical cancer
      2011 - 2012, $25,000
      PI: Ryan Flynn
   4. NSF Cyber-Physical Systems (CPS)
      Rotating Shield Brachytherapy
      Oct. 10, 2012 - Oct 9, 2016, $1,637,503
      Principal investigator: Ryan Flynn, Ph.D. (0% effort)
      
      
   8. Intramural presentations
      
      
      1. Flynn RT, "Image quality improvement with and dosimetry of an MVCBCT imaging beam line," Invited lecture, University of Iowa, Iowa City, IA (March 6, 2009)
      2. Flynn RT, "Improving megavoltage cone beam CT image quality and accounting for imaging dose," Invited lecture, Translational Research Meeting, University of Iowa, Iowa City, IA (April 10, 2009).
      3. Flynn RT, "Improving megavoltage cone beam CT image quality and accounting for imaging dose," Invited lecture, Electrical and Computer Engineering Graduate Seminar, University of Iowa, Iowa City, IA (January 28, 2010).
         Slides
      4. Flynn RT, "Possibilities for tumor monitoring with implantable devices," March 5, 2010, Invited lecture, Translational Research Meeting, University of Iowa, Iowa City, IA.
         Slides
      5. Schwerter A, Guan J, Ying X, Pelland D, Morris A, Flynn RT, "Reducing Excess Imaging Dose to Cancer Patients Receiving Radiotherapy," Spring Undergraduate Research Festival (SURF) at UIowa, Winner of the Distinguished Poster Award in the Natural Sciences (March 27, 2010).
      6. Edwards D, Flynn R, "Using intensity-modulated brachytherapy to treat cervical cancer," Fall Undergraduate Research Festival, University of Iowa, Dec. 8, 2010. D. Edwards was one of 6 undergraduate researchers invited to present at the University of Iowa Board of Trustees meeting on 2/3/2011.
      7. Breitbach EK, Flynn RT, "Image quality improvement in megavoltage cone beam CT using a sintered pixelated array system," Fall Undergraduate Research Festival, University of Iowa, Dec. 8, 2010. Link.
      8. Flynn R, "Intensity Modulated Brachytherapy for Cervical Cancer," Mechanical Engineering Seminar, University of Iowa, Sept. 8, 2011.
         Slides
      9. Flynn R, "Intensity modulated brachytherapy for prostate cancer," Prostate Cancer Research Program, University of Iowa, May 27, 2011.
      10. Edwards DS, Kim Y, Wu X, Flynn R, "Giving Hope to Cervical Cancer Patients with Multiple-Rotating Shield Brachytherapy (MRS-IMBT)," Fall Undergraduate Research Festival, University of Iowa, Dec. 7, 2011. Winner: Outstanding Poster in the Natural Sciences Award.
      11. Flynn R, Kim Y, Wu X, "Intensity modulated brachytherapy for cervical cancer," ECE Graduate Seminar, Jan. 26, 2012.
          Slides
      12. Flynn R, Kim Y, Wu X, "Intensity modulated brachytherapy for cervical cancer," Radiation Oncology Translational Research Meeting, Jan. 27, 2012.
      13. Breitbach E, Adams Q, Davis S, Flynn RT, "A Monte Carlo dose calculation model for intensity modulated brachytherapy radiation sources," Medical Student Research Day Oral Presentation, Sept. 7, 2012. Winner: Larry Oberley Award for Outstanding Oral Presentation.
      14. Adams Q, Flynn RT, "Alternative Radioisotopes for use as radiation sources in rotating-shield brachytherapy," Medical Student Research Day Oral Presentation, Sept. 7, 2012.
          
          
   9. Extramural Invited Lectures, Conference Presentations, Visiting Professorships
      
      
      1. Kowalok M, Jeraj R, Bohm T, Flynn R, Mackie T, Henderson D, "Iterative adjoint and forward Monte Carlo transport for external beam treatment planning," AAPM Annual Meeting, Pittsburgh, PA, Med Phys 31, 1898 (2004).
      2. Flynn R, Jeraj R, Kowalok M, Mackie T, "Construction of a tomotherapy beam model based on thick target bremsstrahlung and Monte Carlo derived parameters," AAPM Annual Meeting, Pittsburgh, PA, Med Phys 31, 1874 (2004).
      3. Mackie T, Flynn R, Kissick M, Jeraj R, "An analysis of intensity discretization errors in IMRT," AAPM Annual Meeting, Seattle, WA, Med Phys 32, 1972 (2005).
      4. Jeraj R, Kowalok M, Flynn R, Mackie TR, "Simulations of an image-guided radiotherapy system," The Monte Carlo Method: Versatility Unbounded in a Dynamic Computing World, Chattanooga, TN, American Nuclear Society, LaGrange Park, IL (2005).
      5. Flynn R, Jeraj R, Mackie T, "A probabilistic method for online treatment plan modification," AAPM Annual Meeting, Seattle, WA, Med Phys 32, 1930 (2005).
      6. Flynn R, Unkelbach J, Oelfke U, Jeraj R, Mackie T, "A comparison of two probabilistic methods for intra-fractional re-optimization in IMRT," Biennial ESTRO Meeting, Lisbon, Portugal, Radiother Oncol 72, S106 (2005).
      7. Mackie T, Kissick M, Flynn R, Westerly D, Hill P, DeLuca P, Jeraj R, Schreuder A, Farr J, "Simultaneous multi-pencil fan-beam-based intensity modulated proton therapy," AAPM Annual Meeting, Orlando, FL, Med Phys 33, 2296 (2006).
      8. Barbee D, Flynn R, Jaskowiak C, Jeraj R, "Effects of PET reconstruction parameters on the delineation of heterogeneous target volumes," AAPM Annual Meeting, Orlando, FL, Med Phys 33, 2242 (2006).
      9. Flynn R, Kissick M, Jeraj R, Mehta M, Olivera G, Srinavasan S, Mackie T, "Propagation of linac output and fluence discretization error to dose distributions in IMRT," AAPM National Meeting, Orlando, FL, Med Phys 33, 2130 (2006).
      10. Becker S, Shaw R, Flynn R, Mackie T, "A novel tomotherapy design for the breast," AAPM Annual Meeting, Orlando, FL, Med Phys 33, 2059 (2006).
      11. Flynn R, Kissick M, Mehta M, Jeraj R, Mackie T, "An investigation of the effects of relatively large linac output variations on dose distributions for IMRT," North Central Chapter of the AAPM Bi-Annual Meeting, Minneapolis, MN (2006).
      12. Flynn RT, Barbee D, Jeraj R, Mackie TR, "A Phantom Study of Selective Subvolume Boosting with Intensity Modulated Proton Therapy and Intensity Modulated X-ray Therapy," Proton Therapy Co-Operative Group (PTCOG) Conference, Wanjie, Zibo, China (2007).
      13. Kissick M, Flynn R, Hoban P, Westerly D, Mackie T, "Optimizing Sharp Longitudinal Tomotherapy Dose Distributions," Proceedings of ICCR International Conference, Abstract 88, Toronto, ON, Canada (2007).
      14. Mackie T, Flynn R, Westerly D, Hill P, Kissick M, Jeraj R, DeLuca P, "Distal Edge Tracking Intensity Modulated Proton Therapy Using a Fan Beam," Proceedings of ICCR International Conference, Toronto, ON, Canada (2007).
      15. Flynn R, Tomé W, Gutiérrez A, Westerly D, Jeraj R, Mackie T, "Whole brain radiation therapy with conformal avoidance of the hippocampus: a comparison of x-ray tomotherapy to proton therapy with distal edge tracking and spot scanning," Proceedings of ICCR International Conference, Toronto, ON, Canada (2007).
      16. Westerly D, Flynn R, Hill P, Mackie T, "Modeling the use of Magnetic Quadrupoles for Ion Fan-Beam Production," Proceedings of ICCR International Conference, Abstract 41, Toronto, ON, Canada (2007).
      17. Kissick M, Flynn R, Westerly D, Jeraj R, Mackie R, "One Vision of the Next Generation of Helical Tomotherapy," 2007 AAPM National Meeting, Minneapolis, MN, Med Phys 34, 2631 (2007).
      18. Mackie T, Caporaso GJ, Chen Y-J, Blackfield D, Harris J, Hawkins S, Holmes C, Nelson S, Paul A, Poole B, Rhodes M, Sanders D, Sullivan J, Wang L, Watson J, Reckwerdt P, Schmidt R, Pearson D, Flynn R, Matthews D, Purdy J, "A Proposal for a Novel Compact Intensity Modulated Proton Therapy System using a Dielectric Wall Accelerator," AAPM Annual Meeting, Minneapolis, MN, Med Phys 34, 2628 (2007).
      19. Bowen S, Flynn R, Bentzen S, Jeraj R, "Effect of a Biologically-based Prescription Function in IMRT Dose Optimization," AAPM Annual Meeting, Minneapolis, MN, Med Phys 34, 2524 (2007).
      20. Flynn R, Barbee D, Bowen S, McCall K, Bentzen S, Mackie T, Jeraj R, "Dose Painting With Intensity Modulated Proton Therapy and Intensity Modulated X-ray Therapy: a Comparison," AAPM Annual Meeting, Minneapolis, MN, Med Phys 34, 2522 (2007).
      21. Flynn RT, Shukla HI, Nixon E, Bayouth JE, "A quantitative assessment of the effects of a simple dead detector pixel correction method for megavoltage cone beam CT images," AAPM Annual Meeting, Houston, TX, Med Phys 35, 2648 (2008).
      22. Bowen SR, Flynn RT, Bentzen SM, Jeraj R, "Impact of Prescription Dose Gradient Discretization on Dose Painting," AAPM Annual Meeting, Houston, TX, Med Phys 35, 2631 (2008).
      23. Barbee DL, Flynn RT, Holden JE, Jeraj R, "Partial volume correction of PET-imaged tumor heterogeneity using expectation maximization," AAPM Annual Meeting, Houston, TX, Med Phys 35, 2976 (2008).
      24. Dirksen BM, Flynn RT, Svare C, Goodin FL, Frigo SP, "Clinical impact of applying heterogeneity correction to dose calculations for esophageal sites," AAPM Annual Meeting, Houston, TX, Med Phys 35, 2834 (2008).
      25. Jeraj R, Simoncic U, Flynn RT, Bowen SR, "Dosimetric differences for dose painting, based on SUV or KFLT FLT-PET image ratio," AAPM Annual Meeting, Houston, TX, Med Phys 35, 2875 (2008).
      26. Kissick MW, Flynn RT, Westerly DC, Hoban PW, Mo X, Soisson ET, McCall KC, Mackie TR, Jeraj R, "The Impact of Longitudinal Breathing Randomness for Tomotherapy Delivery," AAPM Annual Meeting, Houston, TX, Med Phys 35, 2752 (2008).
      27. Flynn RT, "Improving image quality for megavoltage cone beam computed tomography," Invited lecture, Annual meeting of the Japanese Society for Therapeutic Radiology and Oncology (JASTRO), Sapporo, Japan (October 2008).
          Slides
      28. Flynn RT, "Improving image quality for megavoltage cone beam computed tomography," Invited lecture, Siemens User Meeting, Tokyo, Japan (October 2008).
          Slides
      29. Nelms DW, Flynn RT, "Correction of dead detector pixels in 3D imaging for cancer radiation therapy," Presented at Research in the Capitol, Des Moines, IA (March 6, 2009).
      30. Nelms D, Shukla H, Nixon E, Bayouth J, Flynn R, "Quantitative assessment of three dead detector interpolative correction methods for cone beam CT images," AAPM National Meeting, Anaheim, CA, Med Phys 36, 2475 (2009).
      31. Barbee D, Bowen S, Flynn R, Holden J, Jeraj R, "Assessing the impact of partial volume correction on dose painting," AAPM National Meeting, Anaheim, CA, Med Phys 36, 2518 (2009).
      32. Kissick M, Mo X, Westerly D, Flynn R, Bowen S, Schubert L, Jeraj R, Mackie T, "Tomotherapy dose painting delivery robust to respiratory motion," 2009 AAPM National Meeting, Anaheim, CA, Med Phys 36, 2561 (2009).
      33. Huang Y, Flynn R, Siochi R, Bayouth J, "Quality evaluation of unflattened photon beam model," AAPM National Meeting, Anaheim, CA, Med Phys 36, 2673 (2009).
      34. Flynn R, Hartmann J, Bani-Hashemi A, Nixon E, Siochi R, Pennington E, Bayouth J, "Dosimetric characterization of an imaging beam line with a carbon electron target for megavoltage cone beam computed tomography," AAPM National Meeting, Anaheim, CA, Med Phys 36, 2181 (2009).
      35. Bayouth J, Huang Y, Flynn R, "Non-flattened beam planning and delivery for gated hypo-fractionated IMRT in liver cancer," ASTRO Annual Meeting, Chicago, IL, Int J Radiat Oncol*Biol*Phys 75(3), S708 (2009).
      36. Flynn, R, "Loss of radiobiological effect of imaging dose in IGRT due to prolonged imaging-to-treatment time," 10th Biennial ESTRO Conference on Physics and Radiation Technology for Clinical Radiotherapy, Abstract 171, Maastricht, The Netherlands, Radiother Oncol 92(S1), S62 (2009).
      37. Flynn RT, "Improving Megavoltage Cone Beam CT Imaging Quality," University of Wisconsin-Madison Medical Physics Seminar, Feb. 26, 2010.
          Slides
      38. Schwerter A, Guan J, Ying X, Pelland D, Morris A, Flynn RT, "Reducing Excess Imaging Dose to Cancer Patients Receiving Radiotherapy," Presented at Research in the Capitol, Des Moines, IA (March 25, 2010).
      39. Flynn R, Edwards D, Stiles J, Maltz J, Gangadharan B, Bani-Hashemi A, "Image quality improvement in megavoltage cone beam CT using an ultrafast ceramic scintillator system," AAPM Annual Meeting, Philadelphia, PA, Med Phys 37, 3442 (2010).
      40. Schwertner A, Guan J, Ying X, Pelland D, Morris A, Flynn R, "Dosimetric benefits of the imaging dose incorporation (IDI) method for megavoltage cone beam CT (MVCBCT) in head and neck patients," 2010 AAPM National Meeting, Philadelphia, PA, Med Phys 37, 3117 (2010).
      41. Flynn RT, "High dose rate image guided radiation therapy," Invited lecture, JASTRO Koseido Symposium, Shiga, Japan, July 31, 2010.
          Slides
      42. Chesnut D, Flynn RT, Gross B, "Stereotactic body radiotherapy (SBRT) for lung cancer," Invited lecture, ISTRO Annual Meeting, Iowa City, IA, Sept. 18, 2010.
          Slides
      43. Flynn RT, "Stereotactic body radiotherapy guided by optimized megavoltage cone beam computed tomography," 31st Annual Conference of the Association of Medical Physicists of India, Lucknow, India, Nov. 20, 2010. Link
          Slides
      44. Flynn RT, "High dose rate stereotactic body radiotherapy and megavoltage cone beam computed tomography image guidance," 32nd Annual Conference of the Association of Radiation Oncologists of India, Patna, India, Nov. 26, 2010. Link
          Slides
      45. Flynn R, Kim Y, "Compensator-based intensity modulated brachytherapy," 11th Biennial ESTRO Meeting, London, UK (oral presentation). Radiother Oncol 99, S60-61 (2011).
      46. Huang Y, Flynn R, Siochi A, Bayouth J, "Reduction of treatment time in clinical SBRT delivered with unflattened photon beam," 11th Biennial ESTRO Meeting, London, UK. Radiother Oncol 99, S570 (2011).
      47. Edwards DS, Kim Y, Wu X, Flynn RT, "Sequencing method to reduce treatment time for intensity modulated brachytherapy," 2011 Joint AAPM-COMP Meeting, Vancouver, BC, Canada (oral presentation), Med. Phys. 38, 3734 (2011).
      48. Breitbach EK, Maltz JS, Gangadharan BS, Bani-Hashemi AR, Anderson CM, Bhatia SK, Stiles JM, Edwards DS, Flynn RT, "Reducing megavoltage cone beam CT imaging dose without loss of spatial resolution using a sintered pixelated array system," 2011 Joint AAPM-COMP Meeting, Vancouver, BC, Canada (oral presentation), Med. Phys. 38, 3713 (2011).
      49. Flynn RT, Kim Y, Jacobson G, Wu X, "Compensator-based intensity modulated brachytherapy for cervical cancer," 2011 Joint AAPM-COMP Meeting, Vancouver, BC, Canada (poster presentation), Med. Phys. 38, 3668 (2011).
      50. Liu Y, Flynn RT, Kim Y, Wu X, "Optimal sequencing to reduce treatment time while improving the quality of intensity-modulated brachytherapy with fixed-angular fan-beams," 2011 Joint AAPM-COMP Meeting, Vancouver, BC, Canada (poster presentation), Med. Phys. 38, 3686 (2011).
      51. Kissick MW, Flynn RT, Mackie TR, Mo X, Zhao D, Campos D, Yan Y, "The potential of probabilistic optimization for tumor motion with IMRT," 2011 Joint AAPM-COMP Meeting, Vancouver, BC, Canada (poster presentation), Med. Phys. 38, 3684 (2011).
      52. Flynn R, "Preparing for ABR board exams," 2011 Joint AAPM-COMP Meeting, Vancouver, BC, Canada (invited oral presentation), Med. Phys. 38, 3814 (2011).
          Slides, Handout, Evaluation
      53. Liu Y, Flynn R, Kim Y, Wu X, "Dynamic-shield intensity-modulated brachytherapy (IMBT) for cervical cancer," Annual ASTRO Meeting, Miami, FL (poster discussion), Int J Radiat Oncol Biol Phys 81(2), S201 (2011).
      54. Buatti JM, Flynn RT, "Proton Therapy in Iowa City," ISTRO Annual Meeting, Coralville, IA, September 17, 2011.
          Slides
      55. Flynn RT, "Protons in Iowa City," Missouri River Valley AAPM Chapter Meeting, Des Moines, IA, November 5, 2011.
          Slides
      56. Flynn RT, "Introduction to Proton Radiosurgical Considerations," LINAC Radiosurgery, Lake Buena Vista, FL, December 9, 2011.
          Slides
      57. Flynn RT, "Medical Errors in SRT Delivery," LINAC Radiosurgery, Lake Buena Vista, FL, December 10, 2011.
          
          Slides
      58. Flynn RT, "Proton versus photon radiosurgery of intracranial lesions," Invited talk, Western German Proton Therapy Center, Essen, Germany, Jan 20, 2012.
      59. Kim Y, Muruganandham M, Flynn R, Modrick J, Jacobson G, "MRI Guided, Conformal Brachytherapy for Cervical Cancer," Spring AAPM Meeting, 2012.
      60. Edwards DS, Kim Y, Wu X, Flynn R, "Giving Hope to Cervical Cancer Patients With Multiple-Rotating Shield Brachytherapy (MRS-IMBT),” 2012 Research At The Capitol, Iowa State Capitol, April 4, 2012.
      61. Flynn R, "Rotating shield brachytherapy for cervical cancer," Invited talk, Uppsala University, June 8, 2012.
      62. Flynn R, "Preparing for ABR board exams," 2012 AAPM Annual Meeting, Charlotte, NC, (invited oral presentation).
      63. Yang W, Kim Y, Liu Y, Wu X, Flynn R, "Rotating Shield Brachytherapy (RSBT) for Cervical Cancer, 2012 AAPM Annual Meeting, Charlotte, NC.
      64. Liu Y, Flynn R, Yang W, Kim Y, Wu X, "Optimal Emission Angle Selection in Rotating Shield Brachytherapy," 2012 AAPM Annual Meeting, Charlotte, NC.
      65. Bayouth J, Huang Y, Flynn R, Siochi R, "A Clinical Review of the Dosimetric and Temporal Impact of Unflattened X-Ray Beams," 2012 AAPM Annual Meeting, Charlotte, NC.
      66. Flynn R, Buatti J, "Update on the proton therapy program at Iowa," Invited lecture, ISTRO Annual Meeting, Iowa City, IA, October 6, 2012.
          
          
5. SERVICE
   
   
   1. Memberships in Professional Organizations
      
      American Association of Physicists in Medicine (AAPM)
      American College of Medical Physics (ACMP)
      American Society for Therapeutic Radiology and Oncology (ASTRO)
      European Society for Therapeutic Radiology and Oncology (ESTRO)
      
      
   2. Committees
      
      

      Year	Committee
      2007	AAPM Student Physicist Association Subcommittee (SPASC)
      2007 - present	Medical Physics Residency Admissions Committee at UIHC
      2007 - present	Medical Physics Residency Curriculum Committee at UIHC
      2009 - present	Capital Equipment Committee at UIHC
      2009 - 2011	Trainee and Provisional Members Committee for ACMP
      2009 - 2011	Therapy Standards Committee for ACMP
      2010 - present	Physics subcommittee of RSNA Education Exhibits Committee (three-year term)
      2011 - present	AAPM Task Group 180 - Modeling and accounting for the imaging guidance radiation doses to radiotherapy patients in treatment planning

      
      
   3. Refereeing and Associate Editing of journal manuscripts
      
      

      Journal	# Refereed + #Associate edited (Total)	#Refereed + #Associate edited (2013)
      Annals of Oncology	1 + 0	0 + 0
      Journal of Applied Clinical Medical Physics	1 + 0	0 + 0
      Int. J. of Radiat. Oncol.*Biol.*Phys.	3 + 0	1 + 0
      Medical Physics	5 + 7	0 + 0
      Physics in Medicine and Biology	16 + 0	0 + 0
      Radiation Research	1 + 0	0 + 0
      Radiotherapy and Oncology	3 + 0	0 + 0
      Technology in Cancer Research and Treatment	2 + 0	0 + 0

      
      
   4. Reviewing of conference submissions
      
      ACMP Junior Investigators 2010, 2011
      RSNA Educational Exhibit 2011, 2012
      
      
   5. Volunteering
      
      Judge for Medical Student Research Day, Sept 11, 2009; Sept 10, 2010; Sept 7, 2012.
      Judge for College of Engineering 10th Annual Research Open House, April 19, 2012.
      Medical student candidate interviews at UIHC, Fall 2009 (x20), Fall 2010 (x5), Fall 2011 (x10).
      Hope Lodge Dinner, January 20, 2010.