Publications

Kwon, Y.H., Fingert, J.H., Kuehn, M.H., Alward, W.L.M. (2009) Mechanism of Disease: Primary Open Angle Glaucoma. N. Engl. J. Med. 360(11): 1113-1124 PubMed Reprint

Tezel, G., Yang, X., Luo, C, Cai, J., Kain, A.D., Powell, D.W., Kuehn, M.H., Pierce, W.M. (2009) Hemoglobin Expression and Regulation in Glaucoma: Insights into Retinal Ganglion Cell Oxygenation Invest. Ophth. Vis. Sci. In Press PubMed

Lively, G.D., Jiang, B., Hedberg-Buenz, A., Chang, B., Petersen, G.E., Wang, K., Kuehn, M.H., Anderson, M.G. (2009) Genetic Dependence of Central Corneal Thickness among Inbred Strains of Mice. Invest Ophthalmol Vis Sci. In Press PubMed

Grozdanic, S.D., Kecova, H., Harper M.M., Nilaweera, W.U., Kuehn, M.H., Kardon, R.H. (2009) Functional and structural changes in a canine model of hereditary primary angle-closure glaucoma. Invest. Ophth. Vis. Sci. In Press PubMed Reprint

Tezel, G., and the Fourth ARVO/Pfizer Ophthalmics Research Institute Conference Working Group (2009) The role of glia, mitochondria, and the immune system in glaucoma. Invest Ophthalmol Vis Sci. 50(3):1001-12 PubMed Reprint

Kuehn, M.H., Kim, C.Y., Jiang, B, Dumitrescu, A.V., Kwon, Y.H. (2008) Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion. Exp. Eye Res. 87: 89-95 PubMed Reprint

Ostojic J., Grozdanic S.D., Syed, N.A., Hargrove M.S., Trent III J.T., Kuehn M.H., Kwon Y.H., Kardon R.H., and Sakaguchi D.S. (2008) Patterns of Distribution of the Oxygen-Binding Globins, Neuroglobin and Cytoglobin, in Human Retina. Arch. Ophthalmol. 126(11): 1530-6 PubMed

Ostojic J., Grozdanic S.D., Syed, N.A., Hargrove M.S., Trent III J.T., Kuehn M.H., Kwon Y.H., Kardon R.H., and Sakaguchi D.S. (2008) Neuroglobin and Cytoglobin Distribution in the Anterior Eye Segment: a Comparative Immunohistochemical Study J. Histochem. Cytochem. 56: 863-872 PubMed

Mullins, R.F, Kuehn, M.H., Faidley, E.A., Syed, N.A., Stone, E.M. (2007) Differential Macular and Peripheral Expression of Bestrophin in Human Eyes and its Implication for Best Disease. Invest Ophthalmol Vis Sci. 48: 3372-3380 PubMed

Kim, C.Y., Kuehn, M.H., Clark, A.F., and Kwon, Y.H. (2006) Gene Expression Profile of the Adult Human Retinal Ganglion Cell Layer. Mol. Vision 12: 1640-8 PubMed Reprint

Kim, C.Y., Kuehn, M.H., Anderson, M.G., and Kwon, Y.H. (2006) Intraocular Pressure Measurement in Mice: A Comparison between Goldmann and Rebound Tonometry. Eye 20: 1-8 PubMed

Kuehn, M.H, Kim, C.Y., Ostojic, J, Bellin, M, Alward, W.L.M, Stone, E.M., Sakaguchi, D.S., Grozdanic, S.D. Kwon, Y.H. (2006) Retinal synthesis and deposition of complement components induced by ocular hypertension. Exp. Eye Res. 83 (3) 620-8 PubMed Reprint

Mullins, R.F, Skeie, J.M., Malone, E.A, and Kuehn, M.H. (2006) Macular and Peripheral Distribution of ICAM-1 in the Human Choriocapillaris and Retina. Mol. Vis. 12: 224-25 PubMed Reprint

Ostojic J., Sakaguchi D. S., de Lathouder Y., Hargrove M. S., Trent III J. T., Kwon Y.H., Kardon R. H., Kuehn M. H., Betts D. M., and Grozdanic S. D., (2006). Neuroglobin and Cytoglobin: Oxygen-Binding Proteins in Retinal Neurons. Invest Ophthalmol Vis Sci 47: (3) 1016-23 PubMed

Kuehn, M.H., Fingert, J.H., and Kwon, Y.H. (2005) Retinal Ganglion Cell Death in Glaucoma: Mechanisms and Neuroprotective Strategies. Ophthalmol Clin North Am. 18, 383-395 PubMed

Stone, E.M, Braun, T.A., Russell, S.R, Kuehn, M.H., Lotery, A.J., Moore, P.A, Christopher G. Eastman, C.G, Casavant, T.C., and Sheffield, V.C. (2004) Missense Variations in the Fibulin 5 Gene and age-related macular degeneration. N. Engl. J. Med. 351(4): 346-53. PubMed

Kuehn, M.H., Stone, E.S., and Hageman, G.S. (2001) Organization of the Human IPM 200 Gene (IMPG2) and its Evaluation as a Candidate Gene in Age-related Macular Degeneration, Retinitis Pigmentosa and Leber Congenital Amaurosis. Invest. Ophthalmol. Vis. Sci. 13: 3123-3129 PubMed

Alagramam, K.N., Yuan, H., Kuehn, M.H. et al. (2001) Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F. Hum. Mol. Genet. 10: 1709-18. PubMed

Ruiz, A., Kuehn, M.H., Stone, E.S., Hageman, G.S., and Bok, D. (2001) Characterization of the lecithin retinol acyltransferase (LRAT) gene structure and evaluation of it’s involvement in ocular disease. Invest. Ophthalmol. Vis. Sci. 1 : 31-37 PubMed

Kuehn, M.H., Wietecki, D. T., and Hageman, G. S. (2000) Molecular characterization of the murine orthologue of the human retinal proteoglycan IPM 150, Mol. Vis. 6:148-156. PubMed Reprint

Kuehn, M.H. and Hageman, G.S. (1999) Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan. Matrix Biology 18 : 509-518 PubMed

Kuehn, M.H. and Hageman, G.S. (1999) Molecular characterization and genomic mapping of human IPM 200, a second member of a novel family of proteoglycans. Molec. Cell. Biol. Res. Commun 2 : 103-110 PubMed

Gorin, M.B., Breitner, J. C. S., De Jong, P. T. V. M., Hageman, G. S., Klaver, C. C. W., Kuehn, M. H. and Seddon, J. M. (1999) The genetics of age-related macular degeneration. Mol. Vis. 5 : 29 PubMed Reprint

Hageman, G.S., and Kuehn, M.H. (1998) Biology of the retina-IPM-RPE interface, in The Pigmented Retinal Epithelium: Current Aspects of Function and Disease, Marmor, M., and Wolfensberger, T., Eds., Oxford University Press, New York, pp. 417-454